There are now multiple class action lawsuits against the makers of reflux medications like Nexium. There are now multiple studies linking these medications to heart disease, kidney disease, dementia, vitamin deficiencies and more. This was recently posted on Youtube:
An estimated 15 million Americans are currently taking drugs like Nexium which work to control heartburn, indigestion, and acid reflux. Unfortunately, those who turn to Nexium and other Proton-pump inhibitors will need to proceed much more cautiously as studies have confirmed that taking these drugs increase the chance of kidney problems – and even kidney failure – by as much as fifty percent.
Proton-pump inhibitors are a class of drugs which include Nexium, Prilosec, and Prevacid which work by blocking the secretion of acid into the stomach. These extremely common medications are sold both by prescription and over-the-counter. The recent discovery of this increased risk of chronic kidney disease and even failure means that much more care must be taken in determining if a person should be popping the purple pill.
You can also learn safety information on PPIS here.